Vigabatrin is available in Canada only by prescription.

Known as

Sabril

Uses

Used in conjunction with conventional anti-epileptic drugs, vigabatrin is effective in treating partial seizures and partial seizures with secondary generalization. It is also effective in treating some people with Lennox-Gastaut syndrome and West’s syndrome (infantile spasms).

How to Use

Vigabatrin can be taken with food. It should be taken at the same time daily as prescribed.

Side Effects

Common reactions to vigabatrin include drowsiness, tiredness, headaches, stomach upset, weight gain and vision problems.

Precautions

Patients with kidney problems or myoclonic seizures should inform their doctor of these conditions prior to using vigabatrin. Extreme caution should also be used if you are trying to withdraw from this drug. Seek your doctor’s help. Low dosages should be given to patients prone to psychotic behaviours, the elderly and those involved in hazardous tasks and driving. If usual seizures frequency increases, inform your doctor immediately. Vigabatrin should not be used during pregnancy or breastfeeding.

Interactions

When used in combination with the anti-epileptic drug phenytoin, vigabatrin reduces the amount of phenytoin in the blood. Reduce alcohol consumption while taking vigabatrin.

Missed Dose

Take the next dose as soon as you remember. Then resume your usual medication schedule. If you missed a whole day’s medication, consult your doctor.

Storage

Store at room temperature between 15˚C and 30˚C, away from heat, light, moisture and children.

Forms

tablets: 500 mg, white

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