Primidone is available in Canada only by prescription.

Known as

Mysoline, Myidone, Apo-Primidone, Sertan

Uses

Primidone is prescribed, alone or in combination with other anti-epileptic medications to control simple partial, complex partial and tonic-clonic seizures.

How to Use

Take as prescribed. Primidone may be taken with food to prevent stomach upset.

Side Effects

Common reactions include muscular incoordination, dizziness, the sensation of the external world spinning (vertigo), headache, drowsiness, rash and nausea. These usually end after a period of being on the medication.

Precautions

Avoid activities that require mental alertness until you and your doctor agree that your current dosage does not make you drowsy. Regular blood level checks must be done every six months. Older patients with kidney problems must also be monitored periodically. If you are pregnant or breastfeeding an infant, discuss with your doctor whether you should continue to take primidone.

Interactions

Before beginning treatment, inform your doctor of all prescription and over-the-counter medication you are taking. Primidone may

decrease

the action of adrenocorticosteroids, phenytoin, tricyclic depressants, valproic acid and warfarin.

Missed Dose

Take next dose as soon as you remember. Do not double the dose. Resume your regular medication schedule.

Storage

Store at room temperature between 15°C and 30°C. Keep away from children, heat, light and moisture.

Forms

• tablet: 250 mg, white, “AYERST” imprinted on one side
• chewable tablets for children: 125 mg

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